Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Dnmt1  DNA methyltransferase 1   (Synonyms: Cxxc9, Dnmt1o, MommeD2, MTase)
Results	Reference
1*	J:135338 Cirio MC, Ratnam S, Ding F, Reinhart B, Navara C, Chaillet JR, Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints. BMC Dev Biol. 2008;8:9
1	J:321806 Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM, JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency. J Clin Invest. 2022 Mar 1;132(5):e142338
1	J:286844 Kim J, Kim K, Mo JS, Lee Y, Atm deficiency in the DNA polymerase beta null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. Nucleic Acids Res. 2020 Apr 17;48(7):3678-3691
1	J:191599 Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM, Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol. 2012 Dec;132(12):2681-90
1	J:346631 Liu L, Zhang X, Geng HR, Qiao YN, Gui YH, Zhao JY, High paternal homocysteine causes ventricular septal defects in mouse offspring. iScience. 2024 Apr 19;27(4):109447
1	J:341543 Meng TG, Guo JN, Zhu L, Yin Y, Wang F, Han ZM, Lei L, Ma XS, Xue Y, Yue W, Nie XQ, Zhao ZH, Zhang HY, Sun SM, Ouyang YC, Hou Y, Schatten H, Ju Z, Ou XH, Wang ZB, Wong CCL, Li Z, Sun QY, NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition. Adv Sci (Weinh). 2023 Sep;10(27):e2301940
1*	J:46642 Mertineit C, Yoder JA, Taketo T, Laird DW, Trasler JM, Bestor TH, Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development. 1998 Mar;125(5):889-97
1	J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30
1	J:76510 Ratnam S, Mertineit C, Ding F, Howell CY, Clarke HJ, Bestor TH, Chaillet JR, Trasler JM, Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Dev Biol. 2002 May 15;245(2):304-14
1	J:309713 Rhee KD, Yu J, Zhao CY, Fan G, Yang XJ, Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death Dis. 2012 Nov 22;3:e427
1	J:213445 Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ, Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements. PLoS One. 2014;9(2):e88385
1	J:79935 Sakai Y, Suetake I, Itoh K, Mizugaki M, Tajima S, Yamashina S, Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo. Cell Struct Funct. 2001 Dec;26(6):685-91
1	J:345314 Vukic M, Chouaref J, Della Chiara V, Dogan S, Ratner F, Hogenboom JZM, Epp TA, Chawengsaksophak K, Vonk KKD, Breukel C, Ariyurek Y, San Leon Granado D, Kloet SL, Daxinger L, CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses. Sci Adv. 2024 Feb 9;10(6):eadk3384
1	J:144527 Wang J, Hevi S, Kurash JK, Lei H, Gay F, Bajko J, Su H, Sun W, Chang H, Xu G, Gaudet F, Li E, Chen T, The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet. 2009 Jan;41(1):125-9
1	J:310870 Wang W, Zhao X, Shao Y, Duan X, Wang Y, Li J, Li J, Li D, Li X, Wong J, Mutation-induced DNMT1 cleavage drives neurodegenerative disease. Sci Adv. 2021 Sep 3;7(36):eabe8511
1	J:247285 Zhang D, Wu B, Wang P, Wang Y, Lu P, Nechiporuk T, Floss T, Greally JM, Zheng D, Zhou B, Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts. Nucleic Acids Res. 2017 Apr 07;45(6):3102-3115
1*	J:330334 Zhang H, Jiang JC, Wu YW, Yu YS, Wang HN, Ding NZ, Fan HY, The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development. 2022 Oct 1;149(19):dev200497
1	J:344223 Zhang W, Zhang R, Wu L, Zhu C, Zhang C, Xu C, Zhao S, Liu X, Guo T, Lu Y, Gao Z, Yu X, Li L, Chen ZJ, Qin Y, Jiao X, NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Cell Rep. 2023 Dec 26;42(12):113531